It appears this building was built sometime in the 1960s and was, according to the earliest records I've currently accessed, was "Andre's Bicycle Shop". Later on, it became "Bill's Style Shop" at 215 University but eventually Bill retired and the space was absorbed into Zapatos Cantina and after Zapatos closed in 2012, the space that Zapatos had absorbed became Wobbly Monkey, a bar. The original Zapatos section (DoubleDave's) was not part of the deal, but Wobbly Monkey never lasted more than two semesters before the owner sold out. It is now Northgate Juice Joint, which will use part of the outdoor space for an urban garden. Surprisingly, after opening sometime in late 2014, Northgate Juice Joint still operates nearly five years later as of this writing, with "Commanders Cove", an outdoor bar-within-a-store, opening in 2019.
Northgate Juice Joint's current facade is its third since it's been here, the second facade was much more elaborate than the modest one shown in the picture.
Updated June 2020 for University Drive series
UPDATE 07-10-2021: Northgate Juice Joint has since moved to Bryan, with Commanders Cove taking over the space entirely. No other changes to the article have been made.