In the most recent update of this post (November 10th, 2021) we have learned that the subject of the post (split off from this page), Antonio's Pizza by the Slice, closed in very early November 2021 after a run of just short of 18 years, originally opening around November 2003.
Interestingly, Antonio's was actually a branch of an East Coast pizza chain with no locations in New York, but in Massachusetts and New Hampshire, and, until very recently, College Station, Texas.
Back when Antonio's opened, College Main was a normal road with sidewalks, bike lanes, and two functional traffic lanes. That was until College Station decided to turn their half of College Main into a pedestrian mall (the closure happened in summer 2012) while the Bryan side of College Main was made into an attractive roadway with nice lighting, concrete, and bike lanes. The "new" College Main is a charmless void, without even a single tree and basically serves as another bar-hopping plaza like the main Northgate Promenade.
While the building is estimated to date back to 1930, records are spotty. It was Court's University Shoe Repair from until 1979 to the end of 1984. Lacey's (jewelry store) occupied half of the storefront from late 1994 to early 1996, and split the space with Perfect Tan III. Perfect Tan seems to have given way to Software Exchange, which was here from fall 1994 to the end of 1995 and became Byte Me Computers from January 1996 to April 1997, Cycles Etc. from July 1998 to summer 2003 (Cycles Etc. appeared to have occupied the full space). A 1990 planning document also mentions a proposed Thundercloud Subs in the space, but I'm not sure it ever opened. It did however, open next to Albertsons and at 607 University Drive East.
Like many a student, it was Antonio's at my time at A&M, fairly inexpensive (at least prior to 2014), decent-tasting pizza with large slices and, unlike what many of the campus establishments had, Coca-Cola products. Due to varying experiences with the food over the years, I can't really say anything particularly good or bad about it.
UPDATE 11-09-2021: Rewrote entry with better overview of former tenants, and of course, covering the closure of the restaurant ([defunct] label added).
UPDATE 04-02-2022: Added date back to the pedestrian mall as part of reworking original "104-115 College Main" page.
UPDATE 01-13-2023: Dollar Slice Club, a new pizza restaurant, opened in April 2022. [defunct] tag has been removed.